Biocompatible excipient to adjust rheology of solid and liquid dosage forms at small loadings. The large surface area facilitates drug loading in a wide range of drug delivery systems, moreover it can be chemically or physically functionalized for controlled release formulations. 3D nano fibrous network supports wound healing and tissue regeneration in wound dressings and tissue scaffolds.
It is a hot area of research for the tremendous potential of Nanocellulose as a biocompatible & biodegradable material in bio-medical applications.
They are hydrophilic porous soft hydrogels with tunable mechanical properties, and highly expanded surface area. They can be functionalized or grafted with biological molecules, polymers, proteins, drugs, etc.
They are hydrophilic porous soft hydrogels with tunable mechanical properties, and highly expanded surface area. They can be functionalized or grafted with biological molecules, polymers, proteins, drugs, etc.
Main research areas of interest:
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3D Cell culture: 3D soft matrix that mimics ECM (Extra Cellular Matrix), so as to support 3D cell culture for biological investigations and drug screening.
https://doi.org/10.1557/mrc.2017.59, https://doi.org/10.1016/j.biomaterials.2014.03.020 -
Tissue engineering: 3D scaffolds with good mechanical properties, for tissue, cartilage
and bone regeneration in wound healing and tissue engineering.
https://doi.org/10.1557/mrc.2017.59, https://doi.org/10.1016/j.biomaterials.2014.03.020 -
Drug Delivery: NanoCellulose materials can be grafted with biomolecules or chemical agents for specific and controlled drug delivery.
https://doi.org/10.1016/j.ejpb.2012.06.011, https://doi.org/10.1007/s10570-007-9143-y -
Biosensors: NanoCellulose based diagnostics for microbial detection, and physiological signals detection/study.
https://doi.org/10.1016/j.carbpol.2019.04.027, https://doi.org/10.1021/acs.chemmater.7b01170 -
Separation: Separation gels in chromatography for example.
https://doi.org/10.1016/j.jcis.2019.01.017, https://doi.org/10.1021/acs.langmuir.7b00566